A Method of Bone-Metastatic Tumor Progression Assessment in Mice Using Longitudinal Radiography

AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:34:06Z
Fecha de publicación2022-01-01
ResumenMany types of solid tumors metastasize to the bone, where it causes significant morbidity and mortality in patients with advanced disease. Bone metastases are not only incurable but also affect bone health which impairs patients' quality of life. In order to understand the mechanisms and develop effective treatments for bone-metastatic disease, it is first necessary to develop animal models that permit the assessment of tumor growth in the bone and progressive structural changes of the bone simultaneously. Longitudinal analysis of bone tumor progression is generally performed by bioluminescent imaging; however, this method is not able to assess progressive structural changes of the bone. Here, we describe a simple method for assessment of bone lesions using a scoring system that takes into account disease burden and bone destruction using longitudinal radiographs.es_ES
Doihttps://doi.org/10.1007/978-1-0716-1896-7_1es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5871
Idiomaenes_ES
EditorialNLM (Medline)es_ES
RelaciónMethods in molecular biology (Clifton, N.J.)es_ES
URL relacionadohttps://doi.org/10.1007/978-1-0716-1896-7_1es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteMethods in molecular biology (Clifton, N.J.)
Palabra claveBone metastasises_ES
Palabra claveIntrafemoral injectiones_ES
Palabra claveRadiographyes_ES
TítuloA Method of Bone-Metastatic Tumor Progression Assessment in Mice Using Longitudinal Radiographyes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorEber, Matthew R.
AutorJiménez-Andrade, Juan Miguel
AutorPeters, Christopher M.
AutorShiozawa, Yusuke
AutorEber, Matthew R.es_ES
AutorJiménez-Andrade, Juan Migueles_ES
AutorPeters, Christopher M.es_ES
AutorShiozawa, Yusukees_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Rango de páginas1-6es_ES
URL relacionadahttps://doi.org/10.1007/978-1-0716-1896-7_1
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen2413es_ES

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