Coronavirus disease 2019, allergic diseases, and allergen immunotherapy: Possible favorable mechanisms of interaction

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-09-15T00:30:55Z
Fecha de publicación2021-05-01
ResumenBackground:Both, allergen immunotherapy (AIT) and SARS-COV-2 infection cause a set of immunologic changes that respectively vary during the course of the treatment or the disease.Objective:To review immune changes brought along by each of these entities and how they might interrelate.Methods:We start presenting a brief review of the structure of the new coronavirus and how it alters the functioning of the human immune system. Subsequently, we describe the immune changes induced by AIT and how these changes could be favorable or unfavorable in the allergic patient infected with SARS-CoV-2 at a particular point of time during the evolving infection.Results:We describe how a healthy immune response against SARS-CoV-2 develops, versus an immune response that is initially suppressed by the virus, but ultimately overactivated, leading to an excessive production of cytokines (cytokine-storm-like). These changes are then linked to the clinical manifestations and outcomes of the patient. Reviewing the immune changes secondary to AIT, it becomes clear how AIT is capable of restoring a healthy innate immunity. Investigators have previously shown that the frequency of respiratory infections is reduced in allergic patients treated with AIT. On the other hand it also increases immunoregulation.Conclusion:As there are many variables involved, it is hard to predict how AIT could influence the allergic patient's reaction to a SARS-CoV-2 infection. In any case, AIT is likely to be beneficial for the patient with allergic rhinitis and/or allergic asthma in the context of the SARS-CoV-2 pandemic as controlling allergic diseases leads to a reduced need for contact with healthcare professionals. The authors remind the reader that everything in this article is still theoretical, since at the moment, there are no published clinical trials on the outcome of COVID-19 in allergic patients under AIT.es_ES
Doihttps://doi.org/10.2500/aap.2021.42.210013es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/2637
Idiomaenes_ES
EditorialOceanSide Publications, Inces_ES
RelaciónAllergy and Asthma Proceedingses_ES
URL relacionadohttps://doi.org/10.2500/aap.2021.42.210013es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteAllergy and Asthma Proceedings
Palabra claveMedicinees_ES
Palabra claveImmunologyes_ES
Palabra claveImmune systemes_ES
Palabra claveContext (archaeology)es_ES
Palabra claveCytokine stormes_ES
Palabra claveDiseasees_ES
Palabra claveAllergen immunotherapyes_ES
Palabra claveImmunotherapyes_ES
Palabra claveAsthmaes_ES
Palabra claveInnate immune systemes_ES
Palabra claveAllergyes_ES
Palabra claveAllergenes_ES
ClasificaciónCOVID-19 Impact on Reproductiones_ES
TítuloCoronavirus disease 2019, allergic diseases, and allergen immunotherapy: Possible favorable mechanisms of interactiones_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorLarenas‐Linnemann, Désirée
AutorOrtega‐Martell, José Antonio
AutorBlandón-Vijil, María Virginia
AutorRodríguez‐Pérez, Noel
AutorLuna‐Pech, Jorge A.
AutorEstrada-Cardona, Alan
AutorArias‐Cruz, Alfredo
AutorDel-Río-Navarro, Blanca E.
AutorNavarrete-Rodríguez, Elsy M.
AutorPozo-Beltrán, César Fireth
AutorTakane, Ernesto Onuma
AutorRojo-Gutiérrez, María Isabel
AutorEspinosa‐Rosales, Francisco
AutorMartínez, Eric
AutorLarenas‐Linnemann, Désiréees_ES
AutorOrtega‐Martell, José Antonioes_ES
AutorBlandón-Vijil, María Virginiaes_ES
AutorRodríguez‐Pérez, Noeles_ES
AutorLuna‐Pech, Jorge A.es_ES
AutorEstrada-Cardona, Alanes_ES
AutorArias‐Cruz, Alfredoes_ES
AutorDel-Río-Navarro, Blanca E.es_ES
AutorNavarrete-Rodríguez, Elsy M.es_ES
AutorPozo-Beltrán, César Firethes_ES
AutorTakane, Ernesto Onumaes_ES
AutorRojo-Gutiérrez, María Isabeles_ES
AutorEspinosa‐Rosales, Franciscoes_ES
AutorMartínez, Erices_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número3es_ES
Rango de páginas187-197es_ES
URL relacionadahttps://doi.org/10.2500/aap.2021.42.210013
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen42es_ES

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