Allelic frequencies of polymorphisms in genes from AMPK lipid metabolism in Wagyu cattle

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:12Z
Fecha de publicación2025-01-01
ResumenIn cattle, the AMPK pathway acts as an energy sensor that is activated by increases in the cellular AMP/ATP ratio and influences multiple metabolic processes by modifying the FA profile in different tissues. The objective was to estimate and compare the allelic frequencies of 27 SNP in 22 genes of the AMPK pathway, in Wagyu and Wagyu-cross populations. For this, 111 samples of Longissimus dorsi from Wagyu and Wagyu-cross were collected, and grouped by genetic group, 27 SNP located within the 22 genes that participate in the AMPK pathway were typed, linkage disequilibrium, Hardy-Weinberg equilibrium, and the genetic difference between genetic groups were examined. Within the results, 20 polymorphic SNP were found; HNF4 ss61961144 and SCD g.10213 were not found in H-W equilibrium; SNP within SCD1 were found in linkage disequilibrium as were SNPs within PRKAR2A; DGAT1 K232A, IGF2R ss77831885, MYOZ1 ss77831945, PRKAR2A ss62837580, PRKAR2A ss628376667, SCD1 g.10329, SCD5 134718 and SRPRA 4150 presented genetic difference between groups. As conclusions, SCD1 g.10329 is the most solid marker that presents genetic difference between groups, so it can be used in MAS to improve the FA profile in meat. Additionally, it is proposed to perform association analysis with FA of SLC2A4 ss62538460, PLTP ss77832104, PPARGC1A c.1892+19 and MYOZ1 ss77831945, because they are SNP with qualities to be implemented in marker assisted selection, however, they lack further validation of their reported effect.es_ES
Doihttps://doi.org/10.19136/era.a12n3.4237es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5005
Idiomaenes_ES
EditorialUNIV JUAREZ AUTONOMA TABASCO, DIRECCION INVESTIGACION \& POSGRADOes_ES
RelaciónEcosistemas y Recursos Agropecuarioses_ES
URL relacionadohttps://doi.org/10.19136/era.a12n3.4237es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteEcosistemas y Recursos Agropecuarios
Palabra claveFatty acidses_ES
Palabra clavequalityes_ES
Palabra claveBeefes_ES
Palabra clavemolecular markerses_ES
Palabra claveSNPes_ES
TítuloAllelic frequencies of polymorphisms in genes from AMPK lipid metabolism in Wagyu cattlees_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorSanchez-Ramos, Luis Enrique
AutorParra-Bracamonte, Gaspar Manuel
AutorSifuentes-Rincon, Ana Maria
AutorMartinez-Gonzalez, Juan Carlos
AutorMagana-Monforte, Juan G.
AutorVazquez-Armijo, Jose Fernando
AutorRosa-Reyna, Xochitl Fabiola De La
AutorMoreno-Medina, Victor Ricardo
AutorSanchez-Ramos, Luis Enriquees_ES
AutorParra-Bracamonte, Gaspar Manueles_ES
AutorSifuentes-Rincon, Ana Mariaes_ES
AutorMartinez-Gonzalez, Juan Carloses_ES
AutorMagana-Monforte, Juan G.es_ES
AutorVazquez-Armijo, Jose Fernandoes_ES
AutorRosa-Reyna, Xochitl Fabiola De Laes_ES
AutorMoreno-Medina, Victor Ricardoes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número3es_ES
URL relacionadahttps://doi.org/10.19136/era.a12n3.4237
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen12es_ES

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