Cardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Models

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:19Z
Fecha de publicación2023-01-01
ResumenCaffeine is widely used to improve neonatal health in animals with low vitality. Due to its pharmacokinetics and pharmacodynamics, caffeine stimulates the cardiorespiratory system by antagonism of adenosine receptors and alteration in Ca+2 ion channel activity. Moreover, the availability of intracellular Ca+2 also has positive inotropic effects by increasing heart contractibility and by having a possible positive effect on neonate vitality. Nonetheless, since neonatal enzymatic and tissular systems are immature at birth, there is a controversy about whether caffeine is an effective therapy for newborns. This review aims to analyze the basic concepts of caffeine in neonatal animal models (rat and mouse pups, goat kids, lambs, and piglets), and it will discuss the neuroprotective effect and its physiological actions in reducing apnea in newborns.es_ES
Doihttps://doi.org/10.3390/ani13111769es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5132
Idiomaenes_ES
EditorialMDPIes_ES
RelaciónAnimalses_ES
URL relacionadohttps://doi.org/10.3390/ani13111769es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteAnimals
Palabra clavepositive inotropic effectes_ES
Palabra clavehypoxiaes_ES
Palabra clavenewbornes_ES
Palabra clavemethylxanthinees_ES
TítuloCardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Modelses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMota-Rojas, Daniel
AutorVillanueva-Garcia, Dina
AutorHernandez-Avalos, Ismael
AutorCasas-Alvarado, Alejandro
AutorDominguez-Oliva, Adriana
AutorLezama-Garcia, Karina
AutorMiranda-Cortes, Agatha
AutorMartinez-Burnes, Julio
AutorMota-Rojas, Danieles_ES
AutorVillanueva-Garcia, Dinaes_ES
AutorHernandez-Avalos, Ismaeles_ES
AutorCasas-Alvarado, Alejandroes_ES
AutorDominguez-Oliva, Adrianaes_ES
AutorLezama-Garcia, Karinaes_ES
AutorMiranda-Cortes, Agathaes_ES
AutorMartinez-Burnes, Julioes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número11es_ES
URL relacionadahttps://doi.org/10.3390/ani13111769
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen13es_ES

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