Allergen sensitization linked to climate and age, not to intermittent-persistent rhinitis in a cross-sectional cohort study in the (sub) tropics

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:40Z
Fecha de publicación2014-01-01
ResumenBackground: Allergen exposure leads to allergen sensitization in susceptible individuals and this might influence allergic rhinitis (AR) phenotype expression. We investigated whether sensitization patterns vary in a country with subtropical and tropical regions and if sensitization patterns relate to AR phenotypes or age. Methods: In a national, cross-sectional study AR patients (2-70 y) seen by allergists underwent blinded skin prick testing with a panel of 18 allergens and completed a validated questionnaire on AR phenotypes. Results: 628 patients were recruited. The major sensitizing allergen was house dust mite (HDM) (56\%), followed by Bermuda grass (26\%), ash (24\%), oak (23\%) and mesquite (21\%) pollen, cat (22\%) and cockroach (21\%). Patients living in the tropical region were almost exclusively sensitized to HDM (87\%). In the central agricultural zones sensitization is primarily to grass and tree pollen. Nationwide, most study subjects had perennial (82.2\%), intermittent (56.5\%) and moderate-severe (84.7\%) AR. Sensitization was not related to the intermittent-persistent AR classification or to AR severity; seasonal AR was associated with tree (p < 0.05) and grass pollen sensitization (p < 0.01). HDM sensitization was more frequent in children (0-11 y) and adolescents (12-17 y) (subtropical region: p < 0.0005; tropical region p < 0.05), but pollen sensitization becomes more important in the adult patients visiting allergists (Adults vs children + adolescents for tree pollen: p < 0.0001, weeds: p < 0.0005). Conclusions: In a country with (sub) tropical climate zones SPT sensitization patterns varied according to climatological zones; they were different from those found in Europe, HDM sensitization far outweighing pollen allergies and Bermuda grass and Ash pollen being the main grass and tree allergens, respectively. Pollen sensitization was related to SAR, but no relation between sensitization and intermittent-persistent AR or AR severity could be detected. Sensitization patterns vary with age (child HDM, adult pollen). Clinical implications of our findings are dual: only a few allergens -some region specific - cover the majority of sensitizations in (sub) tropical climate zones. This is of major importance for allergen manufacturers and immunotherapy planning. Secondly, patient selection in clinical trials should be based on the intermittent-persistent and severity classifications, rather than on the seasonal-perennial AR subtypes, especially when conducted in (sub) tropical countries.es_ES
Doihttps://doi.org/10.1186/2045-7022-4-20es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5483
Idiomaenes_ES
EditorialWILEYes_ES
RelaciónClinical and Translational Allergyes_ES
URL relacionadohttps://doi.org/10.1186/2045-7022-4-20es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteClinical and Translational Allergy
Palabra claveHouse dust mitees_ES
Palabra clavePollenes_ES
Palabra claveSkin prick testes_ES
Palabra claveAllergic sensitizationes_ES
Palabra claveAllergic rhinitises_ES
Palabra claveIntermittent rhinitises_ES
Palabra clavePersistent rhinitises_ES
Palabra claveSeasonales_ES
Palabra clavePerenniales_ES
TítuloAllergen sensitization linked to climate and age, not to intermittent-persistent rhinitis in a cross-sectional cohort study in the (sub) tropicses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorLarenas-Linnemann, Desiree
AutorMichels, Alexandra
AutorDinger, Hanna
AutorShah-Hosseini, Kijawasch
AutorMoesges, Ralph
AutorArias-Cruz, Alfredo
AutorAmbriz-Moreno, Marichuy
AutorBedolla Barajas, Martin
AutorCerino Javier, Ruth
AutorCid del Prado, Maria de la Luz
AutorCruz Moreno, Manuel Alejandro
AutorGarcia Almaraz, Roberto
AutorGarcia-Cobas, Cecilia Y.
AutorGarcia Imperial, Daniel A.
AutorGarcia Munoz, Rosa
AutorHernandez-Colin, Dante
AutorLinares-Zapien, Francisco J.
AutorLuna-Pech, Jorge A.
AutorMatta-Campos, Juan J.
AutorMartinez Jimenez, Norma
AutorMedina-Avalos, Miguel A.
AutorMedina Hernandez, Alejandra
AutorMonteverde Maldonado, Alberto
AutorLopez, Doris N.
AutorPizano Nazara, Luis J.
AutorRamirez Sanchez, Emmanuel
AutorRamos-Lopez, Jose D.
AutorRodriguez-Perez, Noel
AutorRodriquez-Ortiz, Pablo G.
AutorLarenas-Linnemann, Desireees_ES
AutorMichels, Alexandraes_ES
AutorDinger, Hannaes_ES
AutorShah-Hosseini, Kijawasches_ES
AutorMoesges, Ralphes_ES
AutorArias-Cruz, Alfredoes_ES
AutorAmbriz-Moreno, Marichuyes_ES
AutorBedolla Barajas, Martines_ES
AutorCerino Javier, Ruthes_ES
AutorCid del Prado, Maria de la Luzes_ES
AutorCruz Moreno, Manuel Alejandroes_ES
AutorGarcia Almaraz, Robertoes_ES
AutorGarcia-Cobas, Cecilia Y.es_ES
AutorGarcia Imperial, Daniel A.es_ES
AutorGarcia Munoz, Rosaes_ES
AutorHernandez-Colin, Dantees_ES
AutorLinares-Zapien, Francisco J.es_ES
AutorLuna-Pech, Jorge A.es_ES
AutorMatta-Campos, Juan J.es_ES
AutorMartinez Jimenez, Normaes_ES
AutorMedina-Avalos, Miguel A.es_ES
AutorMedina Hernandez, Alejandraes_ES
AutorMonteverde Maldonado, Albertoes_ES
AutorLopez, Doris N.es_ES
AutorPizano Nazara, Luis J.es_ES
AutorRamirez Sanchez, Emmanueles_ES
AutorRamos-Lopez, Jose D.es_ES
AutorRodriguez-Perez, Noeles_ES
AutorRodriquez-Ortiz, Pablo G.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
URL relacionadahttps://doi.org/10.1186/2045-7022-4-20
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen4es_ES

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