Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groups

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:38Z
Fecha de publicación2018-01-01
ResumenType 2 diabetes (T2D) is a prevalent risk factor for tuberculosis (TB), but most studies on TB-T2D have focused on TB patients, been limited to one community, and shown a variable impact of T2D on TB risk or treatment outcomes. We conducted a cross-sectional assessment of sociodemographic and metabolic factors in adult TB contacts with T2D (versus no T2D), from the Texas-Mexico border to study Hispanics, and in Cape Town to study South African Coloured ethnicities. The prevalence of T2D was 30.2\% in Texas-Mexico and 17.4\% in South Africa, with new diagnosis in 34.4\% and 43.9\%, respectively. Contacts with T2D differed between ethnicities, with higher smoking, hormonal contraceptive use and cholesterol levels in South Africa, and higher obesity in Texas-Mexico (p < 0.05). PCA analysis revealed striking differences between ethnicities in the relationships between factors defining T2D and dyslipidemias. Our findings suggest that screening for new T2D in adult TB contacts is effective to identify new T2D patients at risk for TB. Furthermore, studies aimed at predicting individual TB risk in T2D patients, should take into account the heterogeneity in dyslipidemias that are likely to modify the estimates of TB risk or adverse treatment outcomes that are generally attributed to T2D alone.es_ES
Doihttps://doi.org/10.1016/j.tube.2018.08.007es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5442
Idiomaenes_ES
EditorialCHURCHILL LIVINGSTONEes_ES
RelaciónTuberculosises_ES
URL relacionadohttps://doi.org/10.1016/j.tube.2018.08.007es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteTuberculosis
Palabra claveTuberculosises_ES
Palabra claveDiabeteses_ES
Palabra claveEthnices_ES
Palabra claveMetabolismes_ES
Palabra claveCardiovasculares_ES
Palabra claveCholesteroles_ES
TítuloDiabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groupses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorRestrepo, I, Blanca
AutorKleynhans, Leanie
AutorSalinas, Alejandra B.
AutorAbdelbary, Bassent
AutorTshivhula, Happy
AutorAguillon-Duran, Genesis P.
AutorKunsevi-Kilola, Carine
AutorSalinas, Gloria
AutorStanley, Kim
AutorMalherbe, Stephanus T.
AutorMaasdorp, Elizna
AutorGarcia-Viveros, Moncerrato
AutorLouw, Ilze
AutorGarcia-Oropesa, Esperanza M.
AutorLopez-Alvarenga, Juan Carlos
AutorPrins, John B.
AutorWalzl, Gerhard
AutorSchlesinger, Larry S.
AutorRonacher, Katharina
AutorRestrepo, I, Blancaes_ES
AutorKleynhans, Leaniees_ES
AutorSalinas, Alejandra B.es_ES
AutorAbdelbary, Bassentes_ES
AutorTshivhula, Happyes_ES
AutorAguillon-Duran, Genesis P.es_ES
AutorKunsevi-Kilola, Carinees_ES
AutorSalinas, Gloriaes_ES
AutorStanley, Kimes_ES
AutorMalherbe, Stephanus T.es_ES
AutorMaasdorp, Eliznaes_ES
AutorGarcia-Viveros, Moncerratoes_ES
AutorLouw, Ilzees_ES
AutorGarcia-Oropesa, Esperanza M.es_ES
AutorLopez-Alvarenga, Juan Carloses_ES
AutorPrins, John B.es_ES
AutorWalzl, Gerhardes_ES
AutorSchlesinger, Larry S.es_ES
AutorRonacher, Katharinaes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Rango de páginas10-18es_ES
URL relacionadahttps://doi.org/10.1016/j.tube.2018.08.007
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen113es_ES

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