Micronuclei and sister chromatid exchange in lymphocytes from physicians exposed to ionizing radiation

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:32:38Z
Fecha de publicación2026-01-01
ResumenObjectiveOccupational exposure to ionizing radiation is a known risk factor for genomic instability. This study evaluated whether physicians occupationally exposed to ionizing radiation exhibit higher frequencies of chromosomal alterations compared to unexposed hospital workers, utilizing micronuclei and sister chromatid exchanges as biomarkers.MethodsPeripheral blood samples were analyzed from 50 participants: 25 physicians exposed to ionizing radiation (radiologists) and a control group of 25 sex- and age-matched hospital staff with no history of occupational exposure. The cytokinesis-block micronucleus and sister chromatid exchange assays were employed to assess genomic instability.ResultsNo significant differences were observed in hematological parameters between the two groups. However, the frequencies of both micronuclei and sister chromatid exchanges were significantly higher in the exposed physicians compared to the unexposed control group. Chronic occupational exposure to ionizing radiation is associated with measurable signs of genomic instability. These findings highlight the necessity of implementing regular biomonitoring programs for exposed medical personnel to detect early genetic alterations and mitigate potential health risks.es_ES
Doihttps://doi.org/10.1186/s13104-026-07783-wes_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/4478
Idiomaenes_ES
EditorialSPRINGERNATUREes_ES
RelaciónBMC Research Noteses_ES
URL relacionadohttps://doi.org/10.1186/s13104-026-07783-wes_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteBMC Research Notes
Palabra claveIonizing radiationes_ES
Palabra claveOccupational exposurees_ES
Palabra claveMicronucleies_ES
Palabra claveSister chromatid exchangees_ES
Palabra claveGenomic instabilityes_ES
Palabra claveBiomonitoringes_ES
Palabra claveDNA damagees_ES
TítuloMicronuclei and sister chromatid exchange in lymphocytes from physicians exposed to ionizing radiationes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMeza-Espinoza, Juan Pablo
AutorPatron-Baro, Liliana Itzel
AutorNieto-Marin, Nayeli
Autorde la Herran-arita, Alberto Kousuke
AutorNorzagaray-Valenzuela, Claudia Desiree
AutorCarrillo-Cazares, Tomas Adrian
AutorCervin-Serrano, Salvador
AutorValdez-Sandoval, Jose Johanatan
AutorOsuna-Ramos, Juan Fidel
AutorPicos-Cardenas, Veronica Judith
AutorMeza-Espinoza, Juan Pabloes_ES
AutorPatron-Baro, Liliana Itzeles_ES
AutorNieto-Marin, Nayelies_ES
Autorde la Herran-arita, Alberto Kousukees_ES
AutorNorzagaray-Valenzuela, Claudia Desireees_ES
AutorCarrillo-Cazares, Tomas Adrianes_ES
AutorCervin-Serrano, Salvadores_ES
AutorValdez-Sandoval, Jose Johanatanes_ES
AutorOsuna-Ramos, Juan Fideles_ES
AutorPicos-Cardenas, Veronica Judithes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número1es_ES
URL relacionadahttps://doi.org/10.1186/s13104-026-07783-w
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen19es_ES

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