Anaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cells

AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:39Z
Fecha de publicación2009-01-01
ResumenThe genus Anaplasma (Rickettsiales: Anaplasmataceae) includes obligate tick-transmitted intracellular organisms, Anaplasma phagocytophilum and Anaplasma marginale that multiply in both vertebrate and tick host cells. Recently, we showed that A. marginale affects the expression of tick genes that are involved in tick survival and pathogen infection and multiplication. However, the gene expression profile in A. phagocytophilum-infected tick cells is currently poorly characterized. The objectives of this study were to characterize tick gene expression profile in Ixodes scapularis ticks and cultured ISE6 cells in response to infection with A. phagocypthilum and to compare tick gene expression responses in A. phagocytophilum- and A. marginale-infected tick cells by microarray and real-time RT-PCR analyses. The results of these studies demonstrated modulation of tick gene expression by A. phagocytophilum and provided evidence of different gene expression responses in tick cells infected with A. phagocytophilum and A. marginale. These differences in Anaplasma-tick interactions may reflect differences in pathogen life cycle in the tick cells. Copyright (C) 2009 Zorica Zivkovic et al.es_ES
Doihttps://doi.org/10.1155/2009/705034es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5463
Idiomaenes_ES
EditorialHINDAWI LTDes_ES
RelaciónComparative and Functional Genomicses_ES
URL relacionadohttps://doi.org/10.1155/2009/705034es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteComparative and Functional Genomics
TítuloAnaplasma phagocytophilum and Anaplasma marginale Elicit Different Gene Expression Responses in Cultured Tick Cellses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorZivkovic, Zorica
AutorBlouin, Edmour F.
AutorManzano-Roman, Raul
AutorAlmazan, Consuelo
AutorNaranjo, Victoria
AutorMassung, Robert F.
AutorJongejan, Frans
AutorKocan, Katherine M.
Autorde la Fuente, Jose
AutorZivkovic, Zoricaes_ES
AutorBlouin, Edmour F.es_ES
AutorManzano-Roman, Raules_ES
AutorAlmazan, Consueloes_ES
AutorNaranjo, Victoriaes_ES
AutorMassung, Robert F.es_ES
AutorJongejan, Franses_ES
AutorKocan, Katherine M.es_ES
Autorde la Fuente, Josees_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
URL relacionadahttps://doi.org/10.1155/2009/705034
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES

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