Caffeine: cardiorespiratory effects and tissue protection in animal models

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:27Z
Fecha de publicación2021-01-01
ResumenThe aim of this review is to analyze the cardiorespiratory and tissue-protective effects of caffeine in animal models. Peer-reviewed literature published between 1975 and 2021 was retrieved from CAB Abstracts, PubMed, ISI Web of Knowledge, and Scopus. Extracted data were analyzed to address the mechanism of action of caffeine on cardiorespiratory parameters (heart rate and rhythm), vasopressor effects, and some indices of respiratory function; we close this review by discussing the current debate on the research carried out on the effects of caffeine on tissue protection. Adenosine acts through specific receptors and is a negative inotropic and chronotropic agent. Blockage of its cardiac receptors can cause tachycardia (with arrhythmogenic potential) due to the intense activity of beta 1 receptors. In terms of tissue protection, caffeine inhibits hyperoxia-induced pulmonary inflammation by decreasing proinflammatory cytokine expression in animal models. The protection that caffeine provides to tissues is not limited to the CNS, as studies have demonstrated that it generates attenuation of inflammatory effects in pulmonary tissue. It inhibits the effects of some pro-inflammatory cytokines and prevents functional and structural changes.es_ES
Doihttps://doi.org/10.1538/expanim.20-0185es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5282
Idiomaenes_ES
EditorialINT PRESS EDITING CENTRE INCes_ES
RelaciónExperimental Animalses_ES
URL relacionadohttps://doi.org/10.1538/expanim.20-0185es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteExperimental Animals
Palabra claveanimal modeles_ES
Palabra clavecaffeinees_ES
Palabra clavecardiorespiratory effectes_ES
Palabra clavetissue protectiones_ES
TítuloCaffeine: cardiorespiratory effects and tissue protection in animal modelses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorVillanueva-Garcia, Dina
AutorMota-Rojas, Daniel
AutorMiranda-Cortes, Agatha
AutorIbarra-Rios, Daniel
AutorCasas-Alvarado, Alejandro
AutorMora-Medina, Patricia
AutorMartinez-Burnes, Julio
AutorOlmos-Hernandez, Adriana
AutorHernandez-Avalos, Ismael
AutorVillanueva-Garcia, Dinaes_ES
AutorMota-Rojas, Danieles_ES
AutorMiranda-Cortes, Agathaes_ES
AutorIbarra-Rios, Danieles_ES
AutorCasas-Alvarado, Alejandroes_ES
AutorMora-Medina, Patriciaes_ES
AutorMartinez-Burnes, Julioes_ES
AutorOlmos-Hernandez, Adrianaes_ES
AutorHernandez-Avalos, Ismaeles_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número4es_ES
Rango de páginas431-439es_ES
URL relacionadahttps://doi.org/10.1538/expanim.20-0185
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen70es_ES

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