Control of multiple arthropod vector infestations with subolesin/akirin vaccines

AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:34:23Z
Fecha de publicación2013-01-01
ResumenDiseases transmitted by arthropod vectors such as mosquitoes, ticks and sand flies greatly impact human and animal health and thus their control is important for the eradication of vector-borne diseases (VBD). Vaccination is an environmentally friendly alternative for vector control that allows control of several VBD by targeting their common vector. Recent results have suggested that subolesin/akirin (SUB/AKR) is good candidate antigens for the control of arthropod vector infestations. Here we describe the comparative effect of vaccination with SUB, AKR and Q38 and Q41 chimeras containing SUB/AKR conserved protective epitopes on tick, mosquitoes and sand flies vector mortality, molting, oviposition and/or fertility. We demonstrated that SUB vaccination had the highest efficacy (E) across all vector species (54-92%), Q41 vaccination had the highest vaccine E in mosquitoes (99%) by reducing female survival and fertility, and Q38 vaccination had the highest effect on reducing mosquito (28%) and sand fly (26%) oviposition. The effect of vaccination on different developmental processes in several important arthropod vectors encourages the development of SUB/AKR universal vaccines for the control of multiple vector infestations and reduction of VBD.es_ES
Doihttps://doi.org/10.1016/j.vaccine.2012.12.073es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/6174
Idiomaenes_ES
RelaciónVaccinees_ES
URL relacionadohttps://doi.org/10.1016/j.vaccine.2012.12.073es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteVaccine
Palabra claveAkirines_ES
Palabra claveArthropodes_ES
Palabra claveImmunologyes_ES
Palabra claveMosquitoes_ES
Palabra claveSand flyes_ES
Palabra claveSubolesines_ES
Palabra claveTickes_ES
Palabra claveVaccinees_ES
TítuloControl of multiple arthropod vector infestations with subolesin/akirin vaccineses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMoreno-Cid, Juan A.
AutorPérez de la Lastra, José M.
AutorVillar, Margarita
AutorJiménez, Maribel
AutorPinal, Rocío
AutorEstrada-Peña, Agustín
AutorMolina, Ricardo
AutorLucientes, Javier
AutorGortázar, Christian
Autorde la Fuente, José
AutorAlarcón-Elbal, Pedro M.
AutorDelacour, Sarah
AutorOropeza, Vladimir
AutorRuiz, Ignacio
AutorPrudencio, Carlos R.
AutorGalindo, Ruth C.
AutorAlmazán, Consuelo
AutorNijhof, Ard M.
AutorMangold, Atilio J.
AutorMoreno-Cid, Juan A.es_ES
AutorPérez de la Lastra, José M.es_ES
AutorVillar, Margaritaes_ES
AutorJiménez, Maribeles_ES
AutorPinal, Rocíoes_ES
AutorEstrada-Peña, Agustínes_ES
AutorMolina, Ricardoes_ES
AutorLucientes, Javieres_ES
AutorGortázar, Christianes_ES
Autorde la Fuente, Josées_ES
AutorAlarcón-Elbal, Pedro M.es_ES
AutorDelacour, Sarahes_ES
AutorOropeza, Vladimires_ES
AutorRuiz, Ignacioes_ES
AutorPrudencio, Carlos R.es_ES
AutorGalindo, Ruth C.es_ES
AutorAlmazán, Consueloes_ES
AutorNijhof, Ard M.es_ES
AutorMangold, Atilio J.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número8es_ES
Rango de páginas1187-1196es_ES
URL relacionadahttps://doi.org/10.1016/j.vaccine.2012.12.073
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen31es_ES

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