Control of multiple arthropod vector infestations with subolesin/akirin vaccines
| Audiencia | Público en general | es_ES |
| Cobertura | México | es_ES |
| Fecha de ingreso | 2026-10-05T16:34:23Z | |
| Fecha de publicación | 2013-01-01 | |
| Resumen | Diseases transmitted by arthropod vectors such as mosquitoes, ticks and sand flies greatly impact human and animal health and thus their control is important for the eradication of vector-borne diseases (VBD). Vaccination is an environmentally friendly alternative for vector control that allows control of several VBD by targeting their common vector. Recent results have suggested that subolesin/akirin (SUB/AKR) is good candidate antigens for the control of arthropod vector infestations. Here we describe the comparative effect of vaccination with SUB, AKR and Q38 and Q41 chimeras containing SUB/AKR conserved protective epitopes on tick, mosquitoes and sand flies vector mortality, molting, oviposition and/or fertility. We demonstrated that SUB vaccination had the highest efficacy (E) across all vector species (54-92%), Q41 vaccination had the highest vaccine E in mosquitoes (99%) by reducing female survival and fertility, and Q38 vaccination had the highest effect on reducing mosquito (28%) and sand fly (26%) oviposition. The effect of vaccination on different developmental processes in several important arthropod vectors encourages the development of SUB/AKR universal vaccines for the control of multiple vector infestations and reduction of VBD. | es_ES |
| Doi | https://doi.org/10.1016/j.vaccine.2012.12.073 | es_ES |
| URI | https://riuat.uat.edu.mx/handle/123456789/6174 | |
| Idioma | en | es_ES |
| Relación | Vaccine | es_ES |
| URL relacionado | https://doi.org/10.1016/j.vaccine.2012.12.073 | es_ES |
| Derechos | Acceso restringido / Suscripción (Metadatos de producción científica) | es_ES |
| Licencia | http://purl.org/coar/access_right/c_16ec | es_ES |
| Fuente | Vaccine | |
| Palabra clave | Akirin | es_ES |
| Palabra clave | Arthropod | es_ES |
| Palabra clave | Immunology | es_ES |
| Palabra clave | Mosquito | es_ES |
| Palabra clave | Sand fly | es_ES |
| Palabra clave | Subolesin | es_ES |
| Palabra clave | Tick | es_ES |
| Palabra clave | Vaccine | es_ES |
| Título | Control of multiple arthropod vector infestations with subolesin/akirin vaccines | es_ES |
| Tipo | Artículo | es_ES |
| Arbitrado | Ha sido Arbitrado | es_ES |
| Autor | Moreno-Cid, Juan A. | |
| Autor | Pérez de la Lastra, José M. | |
| Autor | Villar, Margarita | |
| Autor | Jiménez, Maribel | |
| Autor | Pinal, Rocío | |
| Autor | Estrada-Peña, Agustín | |
| Autor | Molina, Ricardo | |
| Autor | Lucientes, Javier | |
| Autor | Gortázar, Christian | |
| Autor | de la Fuente, José | |
| Autor | Alarcón-Elbal, Pedro M. | |
| Autor | Delacour, Sarah | |
| Autor | Oropeza, Vladimir | |
| Autor | Ruiz, Ignacio | |
| Autor | Prudencio, Carlos R. | |
| Autor | Galindo, Ruth C. | |
| Autor | Almazán, Consuelo | |
| Autor | Nijhof, Ard M. | |
| Autor | Mangold, Atilio J. | |
| Autor | Moreno-Cid, Juan A. | es_ES |
| Autor | Pérez de la Lastra, José M. | es_ES |
| Autor | Villar, Margarita | es_ES |
| Autor | Jiménez, Maribel | es_ES |
| Autor | Pinal, Rocío | es_ES |
| Autor | Estrada-Peña, Agustín | es_ES |
| Autor | Molina, Ricardo | es_ES |
| Autor | Lucientes, Javier | es_ES |
| Autor | Gortázar, Christian | es_ES |
| Autor | de la Fuente, José | es_ES |
| Autor | Alarcón-Elbal, Pedro M. | es_ES |
| Autor | Delacour, Sarah | es_ES |
| Autor | Oropeza, Vladimir | es_ES |
| Autor | Ruiz, Ignacio | es_ES |
| Autor | Prudencio, Carlos R. | es_ES |
| Autor | Galindo, Ruth C. | es_ES |
| Autor | Almazán, Consuelo | es_ES |
| Autor | Nijhof, Ard M. | es_ES |
| Autor | Mangold, Atilio J. | es_ES |
| Institución | Universidad Autónoma de Tamaulipas | |
| Institución | Universidad Autónoma de Tamaulipas | es_ES |
| Número | 8 | es_ES |
| Rango de páginas | 1187-1196 | es_ES |
| URL relacionada | https://doi.org/10.1016/j.vaccine.2012.12.073 | |
| Tipo de artículo | Indexado | |
| Tipo de artículo | Indexado | es_ES |
| Volumen | 31 | es_ES |
