Chromosomal Abnormalities in Couples with Reproductive Disorders

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-09-15T00:30:35Z
Fecha de publicación2008-01-01
ResumenAIM: To determine the prevalence of chromosomal abnormalities in couples with reproductive disorders. METHODS: A retrospective study was performed in 939 Mexican couples with reproductive disorders (542 with recurrent fetal loss, 356 with malformed/stillborn children, and 41 with sterility) whose karyotype was established on GTG-banded metaphases. RESULTS: A chromosomal aberration was detected in one partner of 52 couples, including a double translocation carrier; therefore, the prevalence of chromosomally abnormal couples was 5.5%; 31 couples with recurrent fetal loss (31/542, 5.7%), 15 with malformed/stillborn children (15/356, 4.2%), and 6 with sterility (6/41, 14.6%). There were 43 couples with structural rearrangements (29 reciprocal translocations, 10 robertsonian translocations, 2 inversions, 1 insertion, and 1 ring) and 9 with gonosomal aneuploidies. The affected partner was female in 28 (53.8%) and male in 24 (46.2%) couples. In addition, 17 couples (1.8%) with the structural variant inversion 9qh were detected. CONCLUSION: The prevalence of chromosomal abnormalities found in our sample is consistent with figures described in several populations around the world.es_ES
Doihttps://doi.org/10.1159/000147170es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/2541
Idiomaenes_ES
EditorialKarger Publisherses_ES
RelaciónGynecologic and Obstetric Investigationes_ES
URL relacionadohttps://doi.org/10.1159/000147170es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteGynecologic and Obstetric Investigation
Palabra claveChromosomal translocationes_ES
Palabra claveSterilityes_ES
Palabra claveRobertsonian translocationes_ES
Palabra claveKaryotypees_ES
Palabra claveChromosomal rearrangementes_ES
Palabra claveChromosomal inversiones_ES
Palabra claveBiologyes_ES
Palabra claveInfertilityes_ES
Palabra claveGeneticses_ES
Palabra claveGynecologyes_ES
Palabra clavePregnancyes_ES
Palabra claveChromosomees_ES
ClasificaciónPrenatal Screening and Diagnosticses_ES
TítuloChromosomal Abnormalities in Couples with Reproductive Disorderses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMeza-Espinoza, Juan Pablo
AutorAnguiano, Lilia Ortiz
AutorRivera, Horacio
AutorMeza-Espinoza, Juan Pabloes_ES
AutorAnguiano, Lilia Ortizes_ES
AutorRivera, Horacioes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número4es_ES
Rango de páginas237-240es_ES
URL relacionadahttps://doi.org/10.1159/000147170
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen66es_ES

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