Genomewide association analysis of growth traits in Charolais beef cattle1

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-09-15T00:30:32Z
Fecha de publicación2016-10-27
ResumenThe objective of this study was to perform a genomewide association study (GWAS) for growth traits in Charolais beef cattle and to identify SNP markers and genes associated with these traits. Our study included 855 animals genotyped using 76,883 SNP from the GeneSeek Genomic Profiler Bovine HD panel. The examined phenotypic data included birth, weaning, and yearling weights as well as pre- and postweaning ADG. After quality control, 68,337 SNP and 823 animals were retained in the analysis. The association analysis was performed using the principal components method via the egscore function of the GenABEL version 1.8-0 package in the R environment. Eighteen SNP located in 13 BTA were associated with growth traits ( < 5 × 10). The most important genes in these genomic regions were (), (), (), (), and ( [angiotensinase C]), due to their relationships with perinatal and postnatal survival, bone growth, cell adhesion, regulation of adipogenesis, and appetite. In conclusion, this study is the first to describe a GWAS conducted in beef cattle in Mexico and represents a basis for further and future research. This study detected new QTL associated with growth traits and identified 5 positional and functional candidate genes that are potentially involved in variations of the analyzed traits. Future analyses of these regions could help to identify useful markers for marker-assisted selection and will contribute to the knowledge of the genetic basis of growth in cattle and be a foundation for genomic predictions in Mexican Charolais cattle.es_ES
Doihttps://doi.org/10.2527/jas.2016-0359es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/2523
Idiomaenes_ES
EditorialOxford University Presses_ES
RelaciónJournal of Animal Sciencees_ES
URL relacionadohttps://doi.org/10.2527/jas.2016-0359es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteJournal of Animal Science
Palabra claveBiologyes_ES
Palabra claveGenome-wide association studyes_ES
Palabra claveSNPes_ES
Palabra claveBeef cattlees_ES
Palabra claveCandidate genees_ES
Palabra claveGeneticses_ES
Palabra claveQuantitative trait locuses_ES
Palabra claveGenetic associationes_ES
Palabra claveSingle-nucleotide polymorphismes_ES
Palabra clavePhenotypees_ES
Palabra claveGenees_ES
Palabra claveGenotypees_ES
ClasificaciónGenetic and phenotypic traits in livestockes_ES
TítuloGenomewide association analysis of growth traits in Charolais beef cattle1es_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorJahuey‐Martínez, Francisco Joel
AutorParra‐Bracamonte, Gaspar Manuel
AutorSifuentes‐Rincón, Ana María
AutorMartínez-González, Juan Carlos
AutorGondro, Cedric
AutorGarcía-Pérez, Carlos A.
AutorLópez-Bustamante, L. A.
AutorJahuey‐Martínez, Francisco Joeles_ES
AutorParra‐Bracamonte, Gaspar Manueles_ES
AutorSifuentes‐Rincón, Ana Maríaes_ES
AutorMartínez-González, Juan Carloses_ES
AutorGondro, Cedrices_ES
AutorGarcía-Pérez, Carlos A.es_ES
AutorLópez-Bustamante, L. A.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número11es_ES
Rango de páginas4570-4582es_ES
URL relacionadahttps://doi.org/10.2527/jas.2016-0359
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen94es_ES

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