Expanding the chemical space of ester of quinoxaline-7-carboxylate 1,4-di- N -oxide derivatives as potential antitubercular agents
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Royal Society of Chemistry (RSC)
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n
-, and isobutyl esters of quinoxaline-1,4-di-
N
-oxide are effective anti-tuberculosis agents against replicating and non-replicating H37Rv bacilli, with top ten lead compounds being relatively safe with selectivity index values over 70.
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