Tick and Host Derived Compounds Detected in the Cement Complex Substance

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:39Z
Fecha de publicación2020-01-01
ResumenTicks are obligate hematophagous arthropods and vectors of pathogens affecting human and animal health worldwide. Cement is a complex protein polymerization substance secreted by ticks with antimicrobial properties and a possible role in host attachment, sealing the feeding lesion, facilitating feeding and pathogen transmission, and protection from host immune and inflammatory responses. The biochemical properties of tick cement during feeding have not been fully characterized. In this study, we characterized the proteome of Rhipicephalus microplus salivary glands (sialome) and cement (cementome) together with their physicochemical properties at different adult female parasitic stages. The results showed the combination of tick and host derived proteins and other biomolecules such as alpha-Gal in cement composition, which varied during the feeding process. We propose that these compounds may synergize in cement formation, solidification and maintenance to facilitate attachment, feeding, interference with host immune response and detachment. These results advanced our knowledge of the complex tick cement composition and suggested that tick and host derived compounds modulate cement properties throughout tick feeding.es_ES
Doihttps://doi.org/10.3390/biom10040555es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5467
Idiomaenes_ES
EditorialMDPIes_ES
RelaciónBiomoleculeses_ES
URL relacionadohttps://doi.org/10.3390/biom10040555es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteBiomolecules
Palabra clavetickes_ES
Palabra clavecementes_ES
Palabra claveproteomicses_ES
Palabra clavedispersive energy X-ray spectroscopyes_ES
Palabra clavesialomees_ES
Palabra clavecementomees_ES
Palabra clavealpha-gales_ES
TítuloTick and Host Derived Compounds Detected in the Cement Complex Substancees_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorVillar, Margarita
AutorPacheco, Ivan
AutorMerino, Octavio
AutorContreras, Marinela
AutorMateos-Hernandez, Lourdes
AutorPrado, Eduardo
AutorKaren Barros-Picanco, Dina
AutorFrancisco Lima-Barbero, Jose
AutorArtigas-Jeronimo, Sara
AutorAlberdi, Pilar
AutorFernandez de Mera, Isabel G.
AutorEstrada-Pena, Agustin
AutorCabezas-Cruz, Alejandro
Autorde la Fuente, Jose
AutorVillar, Margaritaes_ES
AutorPacheco, Ivanes_ES
AutorMerino, Octavioes_ES
AutorContreras, Marinelaes_ES
AutorMateos-Hernandez, Lourdeses_ES
AutorPrado, Eduardoes_ES
AutorKaren Barros-Picanco, Dinaes_ES
AutorFrancisco Lima-Barbero, Josees_ES
AutorArtigas-Jeronimo, Saraes_ES
AutorAlberdi, Pilares_ES
AutorFernandez de Mera, Isabel G.es_ES
AutorEstrada-Pena, Agustines_ES
AutorCabezas-Cruz, Alejandroes_ES
Autorde la Fuente, Josees_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número4es_ES
URL relacionadahttps://doi.org/10.3390/biom10040555
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen10es_ES

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