Neurological outcomes after corpectomy with autologous grafts versus expandable titanium cages: A pilot study

Simple item page
AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:01Z
Fecha de publicación2026-01-01
ResumenBackground: Vertebral corpectomy is a common surgical technique for spinal decompression and fusion. This retrospective pilot study compares the neurological outcomes of corpectomy using autologous bone grafts versus expandable titanium cages. Methods: In this retrospective pilot study of 40 patients, we compared autologous bone grafts versus expandable cages for single-or multi-level corpectomy. We assessed pre-and postoperative mJOA (Modified Japanese Orthopedic Association) scores. To account for baseline imbalances, we performed analysis of covariance (AN-COVA) adjusting for age and preoperative mJOA, and inverse probability of treatment weighting (IPTW) based on propensity scores. Outcomes included postoperative mJOA, AmJOA, responder rate (>= 2-point improvement), and Hirabayashi recovery rate. Results: Both groups showed significant neurological improvement. Adjusted for preoperative mJOA, the AN COVA model found that the titanium group presented significantly higher postoperative mJOA scores after adjustment (ANCOVA coefficient = +2.50, p = 0.0007). IPTW-weighted regression showed a trend toward greater neurological improvement with titanium (coefficient = +1.75, p = 0.092), with satisfactory covaria te balance. Clinically meaningful recovery was observed in 100\% of titanium cases versus 75\% of autologous cases (p = 0.064). The Hirabayashi recovery rate was also superior with titanium (mean 65.0\%) compared to autologous grafts (mean 45.1\%). Conclusion: Both techniques provided similar and effective neurological outcomes after corpectomy. Our findings suggest that neurological recovery is more strongly influenced by the preoperative severity of the myelopathy than by the surgical system used. Both are viable options for corpectomy and warrant larger-scale studies.es_ES
Doihttps://doi.org/10.1016/j.neucir.2025.500732es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/4867
Idiomaeses_ES
EditorialELSEVIER ESPANA SLUes_ES
RelaciónNeurocirugiaes_ES
URL relacionadohttps://doi.org/10.1016/j.neucir.2025.500732es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteNeurocirugia
Palabra claveCorpectomyes_ES
Palabra claveExpandable cageses_ES
Palabra claveAutograftes_ES
Palabra claveNeurological outcomees_ES
Palabra claveSpinal fusiones_ES
TítuloNeurological outcomes after corpectomy with autologous grafts versus expandable titanium cages: A pilot studyes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorPortillo-Gonzalez, Alexis Manuel
AutorLopez-Valdes, Julio Cesar
AutorVega-Moreno, Daniel Alejandro
AutorMedina-Carrillo, Oscar
AutorIbarra-de la Torre, Abraham
AutorGarcia-Gonzalez, Ulises
AutorPortillo-Gonzalez, Alexis Manueles_ES
AutorLopez-Valdes, Julio Cesares_ES
AutorVega-Moreno, Daniel Alejandroes_ES
AutorMedina-Carrillo, Oscares_ES
AutorIbarra-de la Torre, Abrahames_ES
AutorGarcia-Gonzalez, Uliseses_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número2es_ES
URL relacionadahttps://doi.org/10.1016/j.neucir.2025.500732
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen37es_ES

Files

Collections

Documentación Cientifica