Fat, Cartilage, and Bone Metaplasia in Lungs of Cattle With Caudal Pleural Lesions and Subjacent Interstitial Fibrosis

Simple item page
AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:12Z
Fecha de publicación2019-01-01
ResumenThe changes associated with condemned lungs in cattle with chronic pleural lesions of the caudal lobes were characterized by histology and immunohistochemistry (IHC). Fibroproliferative pleural lesions were microscopically confirmed. Occasionally, the pleural lesions also included adipose, chondroid, and osseous metaplasia that were covered by mesothelial cells, mostly in the absence of inflammation. Other lungs also showed fibrosis in the subpleural interstitium and interlobular septa. In both condemned and noncondemned lungs, immunoreactivity to Wilms tumor 1 (WT1) was normally observed on surface mesothelial cells but not on the submesothelial fibroblasts and myofibroblasts. Conversely, the myofibroblasts beneath the pleura, but not the mesothelial cells, showed immunoreactivity to alpha smooth muscle actin and calponin. However, in the lungs with myofibroblastic foci in the pleura, the proliferated cells maintained WT1 immunoreactivity similar to those of some metaplastic cells. These findings may reflect the plasticity of mesothelial cells in vivo.es_ES
Doihttps://doi.org/10.1177/0300985819837719es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5009
Idiomaenes_ES
EditorialSAGE PUBLICATIONS INCes_ES
RelaciónVeterinary Pathologyes_ES
URL relacionadohttps://doi.org/10.1177/0300985819837719es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteVeterinary Pathology
Palabra clavebovinees_ES
Palabra clavemeat inspectiones_ES
Palabra claveslaughterhousees_ES
Palabra clavepleural lesionses_ES
Palabra claveimmunohistochemistryes_ES
Palabra clavemesotheliumes_ES
Palabra clavemyofibroblastses_ES
Palabra clavepleural metaplasiaes_ES
TítuloFat, Cartilage, and Bone Metaplasia in Lungs of Cattle With Caudal Pleural Lesions and Subjacent Interstitial Fibrosises_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorRamirez-Hernandez, Cecilia
AutorJorge Garcia-Marquez, Luis
AutorDecanini-Arcaute, Horacio
AutorMartinez-Burnes, Julio
AutorRamirez-Romero, Rafael
AutorRamirez-Hernandez, Ceciliaes_ES
AutorJorge Garcia-Marquez, Luises_ES
AutorDecanini-Arcaute, Horacioes_ES
AutorMartinez-Burnes, Julioes_ES
AutorRamirez-Romero, Rafaeles_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número4es_ES
Rango de páginas599-603es_ES
URL relacionadahttps://doi.org/10.1177/0300985819837719
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen56es_ES

Files

Collections

Documentación Cientifica