Toxicity and teratogenicity in zebrafish Danio rerio embryos exposed to chromium

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:32:32Z
Fecha de publicación2021-01-01
ResumenChromium (Cr) is an element present in nature in mineral form. It has a dual effect, both as an essential micronutrient and a carcinogenic agent depending on its chemical form and concentration. It is present in various environmental matrices such as water, soil, and air, coming from natural and anthropogenic sources, and causes harmful effects on biota, ecosystems, and even human beings. This study's objective was to evaluate chromium toxicity and teratogenicity in zebrafish embryos of Danio rerio exposed to chromium through the D. rerio teratology assay (DarTA) test by evaluating spine malformations. To this end, the chromium toxicity curve was calculated from zebrafish embryos exposed to potassium dichromate (K2Cr2O7), and the probit test was used to establish the mean lethal concentration (LC50) and three subtoxic concentrations LC25, LC12.5, and LC6.25 to evaluate the teratogenicity. The results showed that potassium dichromate was statistically positive for the teratogenic effect at the three highest concentrations evaluated. Potassium dichromate exposure causes abnormal embryonic development and teratogenic effects, including severe heart defects in zebrafish embryos. Therefore, we conclude that potassium dichromate is toxic to the zebrafish developmental stages. The finding that potassium dichromate is teratogenic in zebrafish embryos suggests that this metal should be tested and evaluate potential risk in mammalian systems.es_ES
Doihttps://doi.org/10.3856/vol49-issue2-fulltext-2561es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/4358
Idiomaenes_ES
EditorialPONTIFICIA UNIV CATOLICA VALPARAISOes_ES
RelaciónLatin American Journal of Aquatic Researches_ES
URL relacionadohttps://doi.org/10.3856/vol49-issue2-fulltext-2561es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteLatin American Journal of Aquatic Research
Palabra claveDanio rerioes_ES
Palabra claveembryoses_ES
Palabra clavemalformationses_ES
Palabra clavechromiumes_ES
Palabra claveteratogenicityes_ES
Palabra claveembryonic developmentes_ES
TítuloToxicity and teratogenicity in zebrafish Danio rerio embryos exposed to chromiumes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorAntonio Sanchez-Olivares, Marco
AutorCarlos Gaytan-Oyarzun, Juan
AutorJose Gordillo-Martinez, Alberto
AutorPrieto-Garcia, Francisco
AutorElias Cabrera-Cruz, Rene Bernardo
AutorAntonio Sanchez-Olivares, Marcoes_ES
AutorCarlos Gaytan-Oyarzun, Juanes_ES
AutorJose Gordillo-Martinez, Albertoes_ES
AutorPrieto-Garcia, Franciscoes_ES
AutorElias Cabrera-Cruz, Rene Bernardoes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número2es_ES
Rango de páginas289-298es_ES
URL relacionadahttps://doi.org/10.3856/vol49-issue2-fulltext-2561
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen49es_ES

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