Neurocognitive function in adult residents of a mining district in Mexico after reducing manganese exposure: Follow-up after 11 years

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-09-15T00:31:24Z
Fecha de publicación2022-07-21
ResumenBackground: Little is known about the neurotoxic effects of chronic exposure to airborne Mn once exposure has been reduced. The environmentally exposed and the reference adult populations evaluated in 2002 were followed, after an environmental management program (EMP) was implemented to reduce the exposure in a mining district in Mexico. Objective: The aim of this study was to compare the association between exposure to Mn and neurocognitive performance in environmentally exposed and reference groups of adults before and after EMP implementation. Methods: In 2013, the same battery of neurocognitive tests used in the initial study (2002) was applied to 58 adults exposed to airborne Mn and 30 adults from the reference community. A cumulative exposure index (CEI) was estimated for the study population before and after the EMP. Categorical outcomes were analyzed using logistic regression, and the resulting ORs were compared between studies. Continuous outcomes were analyzed using linear regression. All models were adjusted for age, years of education, socioeconomic status and blood lead levels. Results: Exposed adults from the post-EMP study showed an improvement in fine motor and verbal regulation of motor skills (OR < 1) compared to the exposed adults from the pre-EMP study (OR > 1). In both pre- and post-studies, the exposed adults showed a deterioration in their dynamic organization of motor activity compared to the reference group (p < 0.05); however, they showed no significant change in attention and working-memory performance. Discussion: After four years of a significant reduction in airborne Mn levels resulting from EMP implementation, chronically exposed adults showed an improvement in fine motor and verbal regulation of motor skills; however, the remaining areas of their motor and cognitive functions remained impaired.es_ES
Doihttps://doi.org/10.1016/j.scitotenv.2022.157519es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/3043
Idiomaenes_ES
EditorialElsevier BVes_ES
RelaciónThe Science of The Total Environmentes_ES
URL relacionadohttps://doi.org/10.1016/j.scitotenv.2022.157519es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteThe Science of The Total Environment
Palabra claveNeurocognitivees_ES
Palabra claveManganesees_ES
Palabra claveMedicinees_ES
Palabra claveEnvironmental healthes_ES
Palabra claveFunction (biology)es_ES
Palabra claveGerontologyes_ES
Palabra claveMetallurgyes_ES
Palabra claveMaterials sciencees_ES
Palabra claveCognitiones_ES
Palabra claveBiologyes_ES
Palabra clavePsychiatryes_ES
ClasificaciónHeavy Metal Exposure and Toxicityes_ES
TítuloNeurocognitive function in adult residents of a mining district in Mexico after reducing manganese exposure: Follow-up after 11 yearses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorCortez‐Lugo, Marlene
AutorHernández-Bonilla, David
AutorRodríguez‐Agudelo, Yaneth
AutorSolís‐Vivanco, Rodolfo
AutorMoreno-Macías, Hortensia
AutorCortez‐Lugo, Marlenees_ES
AutorSchilmann, Astrid
AutorHernández-Bonilla, Davides_ES
AutorRodríguez‐Agudelo, Yanethes_ES
AutorRodríguez-Dozál, Sandra
AutorSolís‐Vivanco, Rodolfoes_ES
AutorMoreno-Macías, Hortensiaes_ES
AutorMontes, Sergio
AutorSchilmann, Astrides_ES
AutorRodríguez-Dozál, Sandraes_ES
AutorRı́os, Camilo
AutorMontes, Sergioes_ES
AutorRı́os, Camiloes_ES
AutorRiojas‐Rodríguez, Horacio
AutorRiojas‐Rodríguez, Horacioes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Rango de páginas157519-157519es_ES
URL relacionadahttps://doi.org/10.1016/j.scitotenv.2022.157519
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen848es_ES

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