EARLY DIAGNOSIS OF CONGENITAL CRANIOFACIAL DIFFERENCES: A SYSTEMATIC REVIEW OF CURRENT EVIDENCE

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:48Z
Fecha de publicación2025-01-01
ResumenIntroduction: Craniofacial congenital differences (CCDs) impact vital functions and have psychosocial implications. Early diagnosis is crucial to optimize prognosis and quality of life. Objective To analyze the current evidence on the early diagnosis of CCDs, identifying effective methodologies and gaps in knowledge. Materials and Methods: This systematic review was conducted following the PRISMA 2020 guidelines. The literature search included 25 studies published between January 2020 and June 2025, covering a variety of designs, such as cohort studies, diagnostic accuracy studies, and randomized controlled trials (RCTs). The consulted databases were PubMed, Scopus, Web of Science, ScienceDirect, LILACS, and Cochrane Library. Study selection and data extraction were performed independently by two reviewers to ensure the reliability of the information. The methodological quality and risk of bias of the included studies were assessed using specific tools: QUADAS-2 for diagnostic accuracy studies, RoB 2.0 for RCTs, and the Newcastle-Ottawa Scale (NOS) for cohort studies. Finally, the overall certainty of evidence was determined using the GRADE rating system. Results: Prenatal ultrasound showed 75% sensitivity and 98% specificity for cleft lip and palate. Fetal MRI achieved 90% sensitivity and 97% specificity for complex CCDs. Prenatal methods allowed for earlier diagnosis (mean 24 weeks of gestation) and facilitated clinical planning. Evidence of the long-term impact on functional/aesthetic prognosis was limited (very low GRADE). Adverse effects were minimal. Conclusions: Prenatal ultrasound and fetal MRI are useful for the early diagnosis of CCDs, improving clinical management. Rigorous research is needed, especially longitudinal studies, to evaluate long-term prognosis and address global disparities.es_ES
Doihttps://doi.org/10.21142/2523-2754-1304-2025-266es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5585
Idiomaeses_ES
EditorialUniversidad Cientifica del Sures_ES
RelaciónRevista Cientifica Odontologicaes_ES
URL relacionadohttps://doi.org/10.21142/2523-2754-1304-2025-266es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteRevista Cientifica Odontologica
Palabra clavecleft lipes_ES
Palabra clavecleft palatees_ES
Palabra clavecraniofacial abnormalitieses_ES
Palabra claveearly diagnosises_ES
Palabra clavemagnetic resonance imaginges_ES
Palabra claveprenatal ultrasonographyes_ES
TítuloEARLY DIAGNOSIS OF CONGENITAL CRANIOFACIAL DIFFERENCES: A SYSTEMATIC REVIEW OF CURRENT EVIDENCEes_ES
Título alternativoDIAGNÓSTICO TEMPRANO DE DIFERENCIAS CONGÉNITAS CRANEOFACIALES: UNA REVISIÓN SISTEMÁTICA DE LA EVIDENCIA ACTUALes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMatta, Sandra Viviana Cáceres
AutorCarmona, Miguel Ángel Flores
AutorGarcía, Debanhi Samantha Flores
AutorMatta, Sandra Viviana Cácereses_ES
AutorCarmona, Miguel Ángel Floreses_ES
AutorGarcía, Debanhi Samantha Floreses_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número4es_ES
URL relacionadahttps://doi.org/10.21142/2523-2754-1304-2025-266
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen13es_ES

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