Post-elimination surveillance in formerly onchocerciasis endemic focus in Southern Mexico

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:12Z
Fecha de publicación2020-01-01
ResumenBackground All formerly endemic communities of the Southern Chiapas focus of onchocerciasis in Mexico were treated with ivermectin until parasite transmission was eliminated by 2015. Transmission of onchocerciasis did not resume during a period of three years (2012-2014) following the final distribution of ivermectin in 2011; it was thus concluded that transmission remained undetectable without intervention. WHO thus declared the elimination of transmission of onchocerciasis from Mexico in 2015. Methodology/Principal findings From 2016 to the present, post-elimination surveillance (PES) based on examination for suspected onchocercomas was performed in the former Southern Chiapas focus. Each year, over 60\% of the total population (range = 85,347-104,106 individuals) of the formerly endemic communities were examined for onchocercomas. Thirty-four individuals were found harboring suspected onchocercomas in the PES surveys conducted from 2016-2019. Of these, one female of 7 years of age who had immigrated from a formerly endemic focus, harbored an infertile (sterile) female in the suspected onchocercoma; all others were negative. Skin biopsy assessments were performed from March through May 2017 in three communities where the female resided. None of the 83 individuals of the three communities examined by skin biopsy were mf positive. Similarly, none of the biopsies from the individuals were found to contain parasite DNA when tested by polymerase chain reaction-enzyme-linked immunosorbent assay (PCR-ELISA). Conclusions/Significance These provide support to the conclusion that onchocerciasis has been eliminated from Mexico.yes_ES
Doihttps://doi.org/10.1371/journal.pntd.0008008es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5018
Idiomaenes_ES
EditorialPUBLIC LIBRARY SCIENCEes_ES
RelaciónPlos Neglected Tropical Diseaseses_ES
URL relacionadohttps://doi.org/10.1371/journal.pntd.0008008es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuentePlos Neglected Tropical Diseases
TítuloPost-elimination surveillance in formerly onchocerciasis endemic focus in Southern Mexicoes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorFernandez-Santos, Nadia A.
AutorUnnasch, Thomas R.
AutorRodriguez-Luna, Isabel C.
AutorPrado-Velasco, Francisco Gibert
AutorAdeniran, Adebiyi A.
AutorMartnez-Montoya, Humberto
AutorRodriguez-Perez, Mario A.
AutorFernandez-Santos, Nadia A.es_ES
AutorUnnasch, Thomas R.es_ES
AutorRodriguez-Luna, Isabel C.es_ES
AutorPrado-Velasco, Francisco Gibertes_ES
AutorAdeniran, Adebiyi A.es_ES
AutorMartnez-Montoya, Humbertoes_ES
AutorRodriguez-Perez, Mario A.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número1es_ES
URL relacionadahttps://doi.org/10.1371/journal.pntd.0008008
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen14es_ES

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