Comparative routes of oxytocin administration in crated farrowing sows and its effects on fetal and postnatal asphyxia

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:25Z
Fecha de publicación2006-01-01
ResumenOxytocin is used to induce and control parturition; nevertheless, an increase in uterine contractions decreases blood flow and gaseous exchange through the uterus predisposing to intra-partum mortality in pigs. The objective of the present study was to evaluate the effect of different oxytocin administration routes on myometrial activity, fetal intrauterine hypoxia and postnatal asphyxia in crated farrowing sows. Yorkshire x Landrace hybrid sows (n = 300), that were approaching the time of parturition, were randomly assigned into six groups. Each group included 50 sows, 10 for each of the parities from one to five. A 40-IU oxytocin dosage was administered by intramuscular (IM), or intravulvar (IVU) routes, or 20 IU was administered via intravenous (IV) route. Groups 1 (G 1), 3 (G(3)) and 5 (G(5)) were administered 0.9\% saline solution (NaCl) IM, IVU and IV, respectively, whereas groups 2 (G(2)) 4 (G(4)) and 6 (G(6)) were treated with oxytocin IM, IVU and IV, respectively. There was a significantly (P < 0.05) greater number of intra-parturn stillbirths (IPS) for the oxytocin treatments, as compared with the control groups, especially with the IVU and IV routes; a lesser number of IPS and lesser IPS with broken umbilical cords was observed with the IM administration route. Oxytocin and control IV administration resulted in longer farrowing durations. Administration of IV-oxytocin resulted in a greater number (P < 0.05) of intrauterine distressed neonates compared with its corresponding control and interpreted through dips II, a fetal cardiac frequency deceleration which determines acute fetal suffering. Independent of the route of oxytocin administration, the treatments resulted in twice as many dips II compared with the respective control groups. The use of the cardiotocograph proved to be an excellent tool for establishing the oxytocin response dose in farrowing sows. A greater number of piglets born alive, which had undergone bradycardia, also showed severe acidosis and greater meconium staining in oxytocin-treated sows, indicating that the administration time (at birth of the first piglet) as well as the dosage used were not adequate treatment regimens in the present study. Further studies will be conducted to evaluate different dosages and oxytocin administration timing to determine the most desirable treatment regimen to increase myometrial contractibility without compromising fetal welfare and neonatal survival. (c) 2005 Elsevier B.V. All rights reserved.es_ES
Doihttps://doi.org/10.1016/j.anireprosci.2005.04.012es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5251
Idiomaenes_ES
EditorialELSEVIERes_ES
RelaciónAnimal Reproduction Sciencees_ES
URL relacionadohttps://doi.org/10.1016/j.anireprosci.2005.04.012es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteAnimal Reproduction Science
Palabra clavepig-asphyxiaes_ES
Palabra clavefetal monitoringes_ES
Palabra clavecardiotocographes_ES
Palabra claveoxytocines_ES
Palabra claveuterine activityes_ES
Palabra clavefarrowing sowes_ES
TítuloComparative routes of oxytocin administration in crated farrowing sows and its effects on fetal and postnatal asphyxiaes_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMota-Rojas, D
AutorTrujillo, ME
AutorMartínez, J
AutorRosales, AM
AutorOrozco, H
AutorRamírez, R
AutorSumano, H
AutorAlonso-Spilsbury, M
AutorMota-Rojas, Des_ES
AutorTrujillo, MEes_ES
AutorMartínez, Jes_ES
AutorRosales, AMes_ES
AutorOrozco, Hes_ES
AutorRamírez, Res_ES
AutorSumano, Hes_ES
AutorAlonso-Spilsbury, Mes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número1-2es_ES
Rango de páginas123-143es_ES
URL relacionadahttps://doi.org/10.1016/j.anireprosci.2005.04.012
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen92es_ES

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