Meconium aspiration syndrome in mammals

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:34:12Z
Fecha de publicación2019-01-01
ResumenMeconium aspiration syndrome (MAS) is a common obstetric and paediatric problem and is one of the most common causes of neonatal respiratory distress. The pathophysiology of MAS is complex. The underlying mechanism of MAS is fetal hypoxia which causes redistribution of fetal blood, increased intestinal peristalsis and relaxation of the anal sphincter in utero, leading to the passage of meconium into the amniotic fluid. If hypoxia is severe and persistent, the fetus gasps for air, but instead aspirate amniotic fluid contaminated with meconium. Aspiration of meconium produces multiple physiological and structural changes in the neonatal lung which relates partially to the amount of aspirated meconium. The structural and functional sequels of MAS include airways obstruction, atelectasis, chemical pneumonitis, hypoxemia, acidosis, pulmonary hypertension and occasionally death. MAS survivors can develop airway hyperreactivity and nervous sequelae. The morbidity and mortality of human MAS have declined the last decades because of new therapies but remains a major paediatric problem. Although the prevalence and significance of MAS in veterinary medicine have been poorly investigated, there is ample evidence that intrapartum hypoxia in animals also causes meconium expulsion, amniotic staining and aspiration. The lungs of affected animals showed airway obstruction, focal atelectasis and alveolitis. Meconium staining of the skin and aspiration are indicators of fetal or perinatal hypoxia and postnatal respiratory distress in domestic animals. Experimental models have been developed to study the pathogenesis of MAS in laboratory animals. This review focuses on the current concepts of the pathophysiology of MAS in human and veterinary medicine.es_ES
Doihttps://doi.org/10.1079/pavsnnr201914013es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5988
Idiomaenes_ES
EditorialCABI Internationales_ES
RelaciónCAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resourceses_ES
URL relacionadohttps://doi.org/10.1079/pavsnnr201914013es_ES
DerechosAcceso restringido / Suscripción (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_16eces_ES
FuenteCAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources
Palabra claveAnoxiaes_ES
Palabra claveAsphyxiaes_ES
Palabra claveMASes_ES
Palabra claveMeconiumes_ES
Palabra claveNeonatees_ES
TítuloMeconium aspiration syndrome in mammalses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMartínez-Burnes, Julio
AutorMota-Rojas, Daniel
AutorVillanueva-García, Dina
AutorIbarra-Ríos, Daniel
AutorLezama-García, Karina
AutorBarrios-García, Hugo
AutorLópez-Mayagoitia, Alfonso
AutorMartínez-Burnes, Julioes_ES
AutorMota-Rojas, Danieles_ES
AutorVillanueva-García, Dinaes_ES
AutorIbarra-Ríos, Danieles_ES
AutorLezama-García, Karinaes_ES
AutorBarrios-García, Hugoes_ES
AutorLópez-Mayagoitia, Alfonsoes_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
URL relacionadahttps://doi.org/10.1079/pavsnnr201914013
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen14es_ES

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