The Utility of Grimace Scales for Practical Pain Assessment in Laboratory Animals

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:31Z
Fecha de publicación2020-01-01
ResumenSimple Summary Grimace scales for laboratory animals were first reported ten years ago. Yet, despite their promise as pain assessment tools it appears that they have not been implemented widely in animal research establishments for clinical pain assessment. We discuss potential reasons for this based on the knowledge gained to date on their use and suggest avenues for further research, which might improve uptake of their use in laboratory animal medicine. Animals' facial expressions are widely used as a readout for emotion. Scientific interest in the facial expressions of laboratory animals has centered primarily on negative experiences, such as pain, experienced as a result of scientific research procedures. Recent attempts to standardize evaluation of facial expressions associated with pain in laboratory animals has culminated in the development of ``grimace scales{''}. The prevention or relief of pain in laboratory animals is a fundamental requirement for in vivo research to satisfy community expectations. However, to date it appears that the grimace scales have not seen widespread implementation as clinical pain assessment techniques in biomedical research. In this review, we discuss some of the barriers to implementation of the scales in clinical laboratory animal medicine, progress made in automation of collection, and suggest avenues for future research.es_ES
Doihttps://doi.org/10.3390/ani10101838es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5311
Idiomaenes_ES
EditorialMDPIes_ES
RelaciónAnimalses_ES
URL relacionadohttps://doi.org/10.3390/ani10101838es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteAnimals
Palabra clavefacial expressionses_ES
Palabra clavepaines_ES
Palabra clavegrimace scaleses_ES
Palabra clavemicees_ES
Palabra claverates_ES
Palabra claverabbites_ES
TítuloThe Utility of Grimace Scales for Practical Pain Assessment in Laboratory Animalses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorMota-Rojas, Daniel
AutorOlmos-Hernandez, Adriana
AutorVerduzco-Mendoza, Antonio
AutorHernandez, Elein
AutorMartinez-Burnes, Julio
AutorWhittaker, Alexandra L.
AutorMota-Rojas, Danieles_ES
AutorOlmos-Hernandez, Adrianaes_ES
AutorVerduzco-Mendoza, Antonioes_ES
AutorHernandez, Eleines_ES
AutorMartinez-Burnes, Julioes_ES
AutorWhittaker, Alexandra L.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número10es_ES
URL relacionadahttps://doi.org/10.3390/ani10101838
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen10es_ES

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