Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos
| Audiencia | Público en general | es_ES |
| Cobertura | México | es_ES |
| Fecha de ingreso | 2026-09-15T00:29:48Z | |
| Fecha de publicación | 2017-01-01 | |
| Resumen | There are currently about 415 million people with diabetes worldwide, a figure likely to increase to 642 million by 2040. In 2015, Mexico was the second Latin American country and sixth in the world in prevalence of this disorder with nearly 11.5 million of patients. Type 2 diabetes (T2D) is the main kind of diabetes and its etiology is complex with environmental and genetic factors involved. Indeed, polymorphisms in several genes have been associated with this disease worldwide. To estimate the genetic epidemiology of T2D in Mexican mestizos a systematic bibliographic search of published articles through PubMed, Scopus, Google Scholar, and Web of Science was conducted. Just case-control studies of candidate genes about T2D in Mexican mestizo inhabitants were included. Nineteen studies that met the inclusion criteria were found. In total, 68 polymorphisms of 41 genes were assessed; 26 of them were associated with T2D risk, which were located in ABCA1, ADRB3, CAPN10, CDC123/CAMK1D, CDKAL1, CDKN2A/2B, CRP, ELMO1, FTO, HHEX, IGF2BP2, IRS1, JAZF1, KCNQ1, LOC387761, LTA, NXPH1, SIRT1, SLC30A8, TCF7L2, and TNF-α genes. Overall, 21 of the 41 analyzed genes were associated with T2D in Mexican mestizos. Such a genetic heterogeneity compares with findings in other ethnic groups. | es_ES |
| Doi | https://doi.org/10.1155/2017/3937893 | es_ES |
| URI | https://riuat.uat.edu.mx/handle/123456789/1758 | |
| Idioma | es | es_ES |
| Editorial | Wiley | es_ES |
| Relación | BioMed Research International | es_ES |
| URL relacionado | https://doi.org/10.1155/2017/3937893 | es_ES |
| Derechos | Acceso abierto (Metadatos de producción científica) | es_ES |
| Licencia | http://purl.org/coar/access_right/c_abf2 | es_ES |
| Fuente | BioMed Research International | |
| Título | Genetic Epidemiology of Type 2 Diabetes in Mexican Mestizos | es_ES |
| Tipo | Artículo | es_ES |
| Arbitrado | Ha sido Arbitrado | es_ES |
| Autor | García-Chapa, Eiralí Guadalupe | |
| Autor | Leal-Ugarte, Evelia | |
| Autor | Peralta-Leal, Valeria | |
| Autor | Durán-González, Jorge | |
| Autor | Meza-Espinoza, Juan Pablo | |
| Autor | García-Chapa, Eiralí Guadalupe | es_ES |
| Autor | Leal-Ugarte, Evelia | es_ES |
| Autor | Peralta-Leal, Valeria | es_ES |
| Autor | Durán-González, Jorge | es_ES |
| Autor | Meza-Espinoza, Juan Pablo | es_ES |
| Institución | Universidad Autónoma de Tamaulipas | |
| Institución | Universidad Autónoma de Tamaulipas | es_ES |
| Rango de páginas | 1-10 | es_ES |
| URL relacionada | https://doi.org/10.1155/2017/3937893 | |
| Tipo de artículo | Indexado | |
| Tipo de artículo | Indexado | es_ES |
| Volumen | 2017 | es_ES |