Association of polymorphisms in growth hormone and leptin candidate genes with live weight traits of Brahman cattle

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:27Z
Fecha de publicación2016-01-01
ResumenPolymorphisms in candidate genes can produce significant and favorable changes in the phenotype, and therefore are useful for the identification of the best combination of favorable variants for marker-assisted selection. In the present study, an assessment to evaluate the effect of 11 single nucleotide polymorphisms (SNPs) in candidate genes on live weight traits of registered Brahman cattle was performed. Data from purebred bulls were used in this assessment. The dataset included birth (BW), weaning (WW), and yearling (YW) weights. A panel of 11 SNP markers, selected by their formerly reported or apparent direct and indirect association with live weight traits, was included in an assessment previously confirming their minimum allele frequency (< 0.05). Live weights were adjusted BW (aBW), WW (aWW), and YW (aYW) using a generalized linear model, which included the fixed effects of herd and season of birth and the random effect of the sire and year of birth. An SNP in a growth hormone gene (GH4.1) was significantly related to aWW (P = 0.035) with an estimate substitution effect of 3.97 kg (P = 0.0210). In addition, a leptin SNP (LEPg. 978) was significantly associated with aYW (P = 0.003) with an estimate substitution effect of 9.57 kg (P = 0.0007). The results suggest that markers GH4.1 and LEPg. 978 can be considered as candidate loci for assisted genetic improvement programs in Mexican Brahman cattle.es_ES
Doihttps://doi.org/10.4238/gmr.15038449es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5280
Idiomaenes_ES
EditorialFUNPEC-EDITORAes_ES
RelaciónGenetics and Molecular Researches_ES
URL relacionadohttps://doi.org/10.4238/gmr.15038449es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteGenetics and Molecular Research
Palabra claveindicuses_ES
Palabra claveGH4.1es_ES
Palabra claveGrowth traitses_ES
Palabra claveLEPg. 978es_ES
Palabra claveSNPes_ES
TítuloAssociation of polymorphisms in growth hormone and leptin candidate genes with live weight traits of Brahman cattlees_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
AutorHernandez, N.
AutorMartinez-Gonzalez, J. C.
AutorParra-Bracamonte, G. M.
AutorSifuentes-Rincon, A. M.
AutorLopez-Villalobos, N.
AutorMorris, S. T.
AutorBriones-Encinia, F.
AutorOrtega-Rivas, E.
AutorPacheco-Contreras, V. I.
AutorMeza-Garcia, L. A.
AutorHernandez, N.es_ES
AutorMartinez-Gonzalez, J. C.es_ES
AutorParra-Bracamonte, G. M.es_ES
AutorSifuentes-Rincon, A. M.es_ES
AutorLopez-Villalobos, N.es_ES
AutorMorris, S. T.es_ES
AutorBriones-Encinia, F.es_ES
AutorOrtega-Rivas, E.es_ES
AutorPacheco-Contreras, V. I.es_ES
AutorMeza-Garcia, L. A.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número3es_ES
URL relacionadahttps://doi.org/10.4238/gmr.15038449
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen15es_ES

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