Subolesin/Akirin Vaccines for the Control of Arthropod Vectors and Vectorborne Pathogens

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AudienciaPúblico en generales_ES
CoberturaMéxicoes_ES
Fecha de ingreso2026-10-05T16:33:32Z
Fecha de publicación2013-01-01
ResumenDiseases transmitted by arthropod vectors such as mosquitoes, ticks and sand flies greatly impact human and animal health, and therefore, their control is important for the eradication of vectorborne diseases (VBD). Vaccination is an environmentally friendly alternative for vector control that allows control of several VBD by targeting their common vector. Recent results have suggested that subolesin (SUB) and its orthologue in insects, akirin (AKR) are good candidate antigens for the control of arthropod vector infestations and pathogen infection. SUB was discovered as a tick-protective antigen in Ixodes scapularis. Vaccination trials with recombinant SUB/AKR demonstrated effective control of arthropod vector infestations in various hard and soft tick species, mosquitoes, sand flies, poultry red mites and sea lice by reducing their numbers, weight, oviposition, fertility and/or moulting. SUB/AKR vaccination also reduced tick infection with tickborne pathogens, Anaplasma phagocytophilum, A.marginale, Babesia bigemina and Borrelia burgdorferi. The effect of vaccination on different hosts, vector species, developmental stages and vectorborne pathogen infections demonstrated the feasibility of SUB/AKR universal vaccines for the control of multiple vector infestations and for reduction in VBD.es_ES
Doihttps://doi.org/10.1111/tbed.12146es_ES
URIhttps://riuat.uat.edu.mx/handle/123456789/5350
Idiomaenes_ES
EditorialWILEYes_ES
RelaciónTransboundary and Emerging Diseaseses_ES
URL relacionadohttps://doi.org/10.1111/tbed.12146es_ES
DerechosAcceso abierto (Metadatos de producción científica)es_ES
Licenciahttp://purl.org/coar/access_right/c_abf2es_ES
FuenteTransboundary and Emerging Diseases
Palabra claveakirines_ES
Palabra clavesubolesines_ES
Palabra clavetickes_ES
Palabra clavemosquitoes_ES
Palabra claveflyes_ES
Palabra clavemitees_ES
Palabra clavelicees_ES
TítuloSubolesin/Akirin Vaccines for the Control of Arthropod Vectors and Vectorborne Pathogenses_ES
TipoArtículoes_ES
ArbitradoHa sido Arbitradoes_ES
Autorde la Fuente, J.
AutorMoreno-Cid, J. A.
AutorGalindo, R. C.
AutorAlmazan, C.
AutorKocan, K. M.
AutorMerino, O.
AutorPerez de la Lastra, J. M.
AutorEstrada-Pena, A.
AutorBlouin, E. F.
Autorde la Fuente, J.es_ES
AutorMoreno-Cid, J. A.es_ES
AutorGalindo, R. C.es_ES
AutorAlmazan, C.es_ES
AutorKocan, K. M.es_ES
AutorMerino, O.es_ES
AutorPerez de la Lastra, J. M.es_ES
AutorEstrada-Pena, A.es_ES
AutorBlouin, E. F.es_ES
InstituciónUniversidad Autónoma de Tamaulipas
InstituciónUniversidad Autónoma de Tamaulipases_ES
Número2, SIes_ES
Rango de páginas172-178es_ES
URL relacionadahttps://doi.org/10.1111/tbed.12146
Tipo de artículoIndexado
Tipo de artículoIndexadoes_ES
Volumen60es_ES

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